The best evidence that ALA can protect the heart comes from the Lyon Diet Heart Study, a randomized clinical trial in Europe. It tested the effects of an ALA-enriched Mediterranean diet in 605 patients with coronary artery disease. Over a four-year period, the high-ALA diet produced a 72% reduction in heart attacks and cardiac deaths and a 56% lower risk of dying from any cause (including cancer). The Mediterranean diet differed from the standard Western diet in many respects, but because it contained a special canola oil margarine, the greatest difference was in its ALA content, which was nearly eight times higher in the protective diet.
To achieve these goals, cut down on saturated fat from animal products (meat and the skin of poultry, whole-fat dairy products, and certain vegetable foods — palm oil, palm kernel oil, cocoa butter, and coconut). And it's just as important to reduce your consumption of trans fatty acids, the partially hydrogenated vegetable oils found in stick margarine, fried foods, and many commercially baked goods and snack foods.
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